In the graph, moisture profiles are shown for desiccated tablets (to maintain the same moisture status) tested on consecutive days. The table shows the measured WVEP and the Precision that is achieved.
When a change in moisture status has occurred, often due to moisture ingress, then a change in the Moisture Profile is seen, resulting in a different Water Vapour Equilibrium Point (WVEP).
See our poster “Study of a Range of Blister Packaging Materials Using the New Technique of Moisture Profiling to Give Early Indications of Moisture Barrier Properties” that shows how the barrier effectiveness in three types of packaging were differentiated in just one day at ICH Q1A(R) real time and accelerated stability conditions.